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Colgate Sensitive Pro-Relief Complete Protection sensitivity toothpaste is clinically proven for instant and lasting relief from sensitivity pain. Click & Collect. The participants with self-reported sensitivity in teeth were clinically diagnosed with DH. The treatment difference between Pro-argin and 8% strontium acetate was not statistically significant with a p>0.05 for immediate and sustained pain relief in DH and statistically significant relative to control on all clinical parameters of the SCASS and VAS. Ashwini S, Swatika K, Kamala DN. 0:00 / 0:30 Colgate Sensitive Pro-Relief Challenge Advert April 2012 178,990 views Mar 29, 2012 Take the Colgate Sensitive Pro-Relief Challenge to Show more 15 Dislike Share. 1Intervention for Group A denotes BioMin F. 2Intervention for Group B denotes Colgate Sensitive Pro relief. 2019;88:103170. For instant relief, apply directly to each sensitive tooth surface and massage for one minute, up to twice a day. Tandkrmen innehller zink fr att strka tandkttet och frhindra att tandkttet drar sig tillbaka, vilket r en av de vanligaste orsakerna till att . In addition, the frequency of participants diagnosed with DH using air blast stimulus was observed as 36.8% at the time of enrolment in the six-week clinical trial that was found consistent with findings of a survey report demonstrating 36.4% frequency of DH among adults in Karachi, Pakistan [24]. Further, it leaves a durable, mineral-enriched layer on the exposed dentin to help protect against future dentin hypersensitivity. These ingredients resulted in rapid fluorapatite crystallisation at exposed tubular ends of dentin [12]. There is no problem with every day and prolonged use. A total of 140 met the eligibility criteria with at least two sensitive teeth anterior to molars due to erosions or abrasions with or without an associated gingival recession. * For instant relief, apply directly to the sensitive tooth with finger tip and gently massage for 1 minute. Dentine hypersensitivity. Patel VR, Shettar L, Thakur S, Gillam D, Kamala DN. https://doi.org/10.1186/s12903-021-01864-x, DOI: https://doi.org/10.1186/s12903-021-01864-x. Product Information. Innehll Colgate Sensitive Instant Relief Enamel Repair r en fluortandkrm med Pro-Argin-teknologi som ger omedelbar smrtlindring vid ilningar i tnderna. The second objective of the current study was to directly compare the clinical efficacy of FCPS, Pro-argin technology, and strontium acetate-based dentifrices due to their similar mode of action and tubular occluding potential in managing DH [36, 37]. Dentine Hypersensitivity. [33] again reported a 54% clinical reduction in DH with Pro-argin in eight weeks clinical trial using SCASS. Privacy Colgate Sensitive Pro-Relief Whitening Toothpaste provides clinically proven instant and lasting relief for sensitive teeth. See patient relevant information on Colgate.com. This toothpaste contains a unique formula that blocks the pathways to pain instantly Its clinically proven formula provides INSTANT RELIEF from the first usage, LONG-LASTING RELIEF with twice everyday use. Identifier NCT 04249336. Colgate Sensitive Pro Relief was compared to a leading brand of desensitizing toothpaste containing stannous fluoride in a laboratory study, with confocal laser scanning microscopy and a novel imaging program used to qualify dentinal tubule occlusion. 2016;3(1):0504. Book They don't. J Dent. Get the freedom to forget about tooth sensitivity with Colgate Sensitive Pro-Relief Complete Protection Toothpaste. In addition, they were responding to air-blast stimulus on the Schiff cold air sensitivity scale (SCASS) with scores2 [22]. Benefits: Colgate Sensitive Prevent and Repair is clinically proven to provide superior relief vs Sensodyne Extra Whitening at 8 weeks1 Long-lasting relief from hypersensitivity with continued use Superior sensitivity relief at 8 weeks vs the leading Sensodyne toothpaste variant 1 This clinical trial was approved by the Institutional Review Board of Dow University of Health Sciences (Ref: IRB-1351/DUHS/Approval/2019/184) and was registered under the protocol ID NCT04249336 (https://clinicaltrials.gov/ct2/show/NCT04249336) on January 30, 2020, in accordance with the CONSORT statement of the updated guidelines for reporting randomised clinical trials. CONSORT flow chart. Docimo R, Montesani L, Maturo P, Costacurta M, Bartolino M, DeVizio W, Zhang YP, Cummins D, Dibart S, Mateo LR: Comparing the Efficacy in Reducing Dentine Hypersensitivity of a New Toothpaste Containing 8.0% Arginine, Calcium Carbonate, and 1450 ppm Fluoride to a Commercial Sensitive Toothpaste Containing 2% Potassium Ion: An Eight-Week Clinical Study in Rome, Italy. Participants were asked to pick up the envelope from the box. compared Colgate Sensitive Pro Relief to another leading brand that desensitizes with a 2% potassium ion formula. J Evid Based Dent Pract. Another meta-analysis by Hu et al. Besides, these findings of the current study could be related to previously conducted clinical trials indicating the better clinical effectiveness of Pro-argin than strontium acetate against air-blast and tactile stimulus after three days and one week of application [30, 31]. Brush twice daily. 3Intervention for Group C denotes Sensodyne Rapid Action. Pashley D. Consensus-based recommendations for the diagnosis and management of dentin hypersensitivity. However, FCPS formulation showed 1% more improvement than Pro-argin and 7% more than strontium acetate-based dentifrices. This clinical trial has not included a run-in or washout period before the test phase due to time constraints and compliance of the potential participants. Arginine, Calcium Carbonate, Aqua, Sorbitol, Aroma, Poloxamer 407, Sodium Monofluorophosphate, Cocamidopropyl betaine, Zinc oxide, Benzyl Alcohol, Cellulose Gum, Zinc Citrate, Sodium Bicarbonate, Tetrasodium Pyrophosphate, Xantham Gum, Sodium Saccharin, Sucralose, Limonene, CL77891, 1. A randomised, controlled, triple-blinded clinical trial was conducted with 140 participants clinically diagnosed with DH and equally randomized into four groups with parallel treatment assignment of FCPS, Pro-Argin, 8% strontium acetate, and sodium fluoride-based OTC dentifrices, and tested for DH with air blast, mechanical, and water jet stimuli on SCHIFF cold air sensitivity scale (SCASS) and visual analogue scale (VAS) at interim efficacy intervals of one minute, three days, two, four, and six weeks, subsequently. J Clin Dent. Mantzourani M, Sharma D. Dentine sensitivity: past, present and future. J Clin Periodontol. It improves gum health and helps reduce factors that contribute to gum recession, a leading cause of tooth sensitivity. With its unique Pro-Argin technology, this sensitive toothpaste will give you instant* relief from sensitivity as it helps to seal and repair the sensitive areas of your teeth. YYYY Colgate-Palmolive Company. For lasting relief and gum protection, apply twice daily using a sensitive toothbrush, making sure to brush all surfaces of teeth including sensitive areas. Compend Contin Educ Dent. Colgate Sensitive Pro-Relief efektywnie i szybko znosi nadwraliwo zbw, zamyka kanaliki zbinowe w ktrych s zakoczenia nerww, dziki czemu blokuje bl. CONCLUSION: The study results support the following conclusions: (1) Colgate Sensitive Pro-Relief toothpaste provides a significantly more reduction in dentin hypersensitivity than Sensodyne. After six weeks, Pro-argin-based dentifrices showed greater clinical efficacy with mean scores (2.151.92) than other treatment arms for mechanical stimulated DH. Colgate Sensitive PRO-Relief Provides clinically proven, everyday protection from painful sensitivity. With regular use, it reduces teeth sensitivity and helps to strengthen gums and prevent gum recession. Dent Health Curr Res. A 3-day randomised clinical study investigating the efficacy of two toothpastes, designed to occlude dentine tubules, for the treatment of dentine hypersensitivity. With the exclusive Pro-Argin formula, it provides instant* and lasting** relief by plugging the channels to block tooth sensitivity. Individuals either with dental caries, heavily restored, or cracked teeth, or with orthodontic or prosthetic appliances, or with localised or generalised gingivitis or pulpitis and heavy calculus or using any desensitising toothpaste or mouth wash or any other desensitising products up to six weeks before the study were excluded from this trial. This binds to the negatively charged dentine surface like a magnet. J Clin Periodontol 42 (2015), 17, 4. Work with Colgate Professional to help provide better oral care to your patients. Helps repair teeth by forming a mineral layer that re-constructs the sensitive part of the tooth, with regular use; Seals the open nerve channels for instant relief, and helps prevent sensitivity from re-occurring; Plus the freshness you trust from Colgate For lsting relief, apply to a gentle toothbrush making sure to brush all . It was found statistically significant relative to control on all clinical parameters of the SCASS and VAS. Comparative evaluation of desensitizing efficacy of dentifrice containing 5% fluoro calcium phosphosilicate versus 5% calcium sodium phosphosilicate: a randomized controlled clinical trial. For children 6-12 years of age, once a week or less frequently. HOW LONG CAN A PATIENT USE Colgate SENSITIVE INSTANT Relief Repair & Prevent? Soft tissues were isolated with cotton rolls, and adjacent teeth were isolated with cotton pellets. Apotekets varuid 29483 Varunummer 207000 Kategori Tandkrm, Ilningar i tnderna Varumrke Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. Venkataramana S, Jeyaraman SK, Kothimbakkam SSK, Chellathurai BNK. These measures facilitated behaviour modification together with the promotion of knowledge and understanding in the society about DH. Pro-Argin technology provides instant* and long-lasting, Oral Care Products | Colgate Professional. More robust trials with a large number of participants are recommended for furtherassessing the impact of DH on the oral health-related quality of life and the difference in the effectiveness of treatments. BMC Oral Health A meta-analysis by Matranga et al. The secondary analysis population could be described as 20 participants per treatment group out of 35 enrolled in the six-week trial who responded to mechanical and water jet stimuli on VAS with scores of4 as secondary outcome measures. We provided oral hygiene instructions and ways of relieving their pain from DH to improve their quality of life. The mean scores with repeated measures were statistically analysed at each time point for study outcomes. Use regularly to enjoy long-lasting relief from sensitivity*. 75 ml. Colgate SENSITIVE INSTANT Relief Repair & Prevent toothpaste with PRO-ARGIN Technology and Zinc provides clinically proven instant* and lasting sensitivity relief1-2 plus lasting gum protection3. The strength of this study was that participants were randomised into four treatment groups to generalise the results for the population [32]. Participants were recalled at interim efficacy intervals of three days, two weeks, four weeks, and six weeks for assessment of sustained relief. Cunha-Cruz J, Wataha JC. The effectiveness of Colgate SENSITIVE INSTANT Relief toothpaste is built on its Pro-Argin technology with arginine and calcium from calcium carbonate. For instant relief, just apply directly to the sensitive tooth with fingertip and gently massage for one minute. The second null hypothesis was that mean scores for pain due to DH among different treatment groups for sustained relief remains the same, and it was considered to be rejected at a p value0.05. 2017;71:18. Compared to stannous fluoride/sodium fluoride and novamin/sodium fluoride. Schiff T, Delgado E, Zhang Y, Cummins D, DeVizio W, Mateo L. Clinical evaluation of the efficacy of an in-office desensitizing paste containing 8% arginine and calcium carbonate in providing instant and lasting relief of dentin hypersensitivity. Dentifrices-containing Pro-argin showed a significant reduction in DH with mean scores of (4.201.70) followed by strontium acetate (4.651.87) followed by FCPS (5.101.88) one minute after application. Formulated with Pro-Argin technology, Colgate Sensitive Pro-Relief is clinically proven instant and lasting sensitivity relief*. Colgate Sensitive Pro Relief Enamel Repair to strengthen weakened enamel and prevent enamel loss. We found more change in pain scores of VAS used for mechanical stimuli with Pro-argin than FCPS as shown in Table 5 that could be relatable with a randomised controlled trial of FCPS and arginine based desensitizers reporting better treatment response of arginine than FCPS in the cold stimulated DH after two weeks to one month, subsequently [40]. 1):8A-15A. Bae J-H, Kim Y-K, Myung S-K. Desensitizing toothpaste versus placebo for dentin hypersensitivity: a systematic review and meta-analysis. However, strontium acetate can potentially obliterate dentinal tubules by replacing the calcium ions of hydroxyapatite crystal lattice structure withstrontium ions along with its nerve depolarisation treat DH [7]. Pak Oral Dent J. J Clin Periodontol. compared the Pro-Argin formulation with a calcium sodium phosphosilicate toothpaste, demonstrating 88% versus 50% occlusion respectively. Two double-blind randomized clinical studies by Nathoo et al. Hu ML, Zheng G, Lin H, Yang M, Zhang YD, Han JM. Panagakos F, Schiff T, Guignon A. Dentin hypersensitivity: effective treatment with an in-office desensitizing paste containing 8% arginine and calcium carbonate. [16] in a systematic review in 2015. Our study included an Asian population, and most of the published literature was associated with the Caucasian population. 75 ml. Yang ZY, Wang F, Lu K, Li YH, Zhou Z. Arginine-containing desensitizing toothpaste for the treatment of dentin hypersensitivity: a meta-analysis. *with direct application and daily brushing. 2008;29(8):1S-35S. We discuss how this innovative technology works to provide patients with rapid and long-lasting relief from dentin hypersensitivity. These outcomes were found in concordance with the previous controlled clinical trial conducted by Patel et al. The probable reason for variations between this clinical trial and previously conducted studies could be attributed to racial or ethnic differences between the conducted trials. Instant relief when applied directly to the sensitive tooth with the fingertip and gently massaged for 1 minute. Most sensitive toothpastes primarily numb the discomfort, whereas Colgate Sensitive Pro-Relief works to relieve sensitivity by plugging the channels that lead to sensitive tooth nerves. With regular use, it creates a long-lasting protective barrier that acts as a seal against sensitivity. All rights reserved. COLGATE. Significantly greater sensitivity reduction with twice - daily brushing compared to control toothpaste with potassium ions. All authors read and approved the final manuscript. Innehller slipmedel med ltt polerande effekt p flckar samt fluor som minskar risken fr karies. Treatment difference between FCPS, Pro-argin, and 8% strontium acetate was not statistically significant with a p>0.05 for sustained pain relief in DH. While 8% strontium acetate showed a greater clinical reduction in water jet stimulated DH on VAS than Pro-argin at all efficacy intervals, as demonstrated in Table 6. These commercially available tooth paste are one n the same thing.Both says they work in reducing the tooth senstivity due to cold intake.These may help olny during the early stages but when there is sensation to both cold and hot drinks and pain, you need to visit a dentist. J Non Cryst Solids. Dentin hypersensitivity can have significant detrimental effects on your patients wellbeing and quality of life. 2020;99(5):51422. The study's primary objective was to investigate pain relief in one minute after topical application of Pro-argin and strontium acetate on sensitive teeth in DH. Google Scholar. The outcomes are in concordance with the previous studies conducted by Layer and Hughes [26], Zang and Shaw [27], and Mason et al. The findings agreed with another in vitro trial by Mahmoodi et al. Akber A, Ali NS, Shabbir S, Wahid U, Farooqui WA. Gently removes stains and helps restore the natural whiteness of your teeth. Dentin hypersensitivity (DH) is a sharp toothache that influences a patients' oral health-related quality of life. Samueli A, Hill R, Gillam D. Bioactive glasses in the management of dentine hypersensitivity: a review. The total sample size was 140 participants, with thirty-five in each group. Vu Pham T, Anh Nguyen T. Clinical evaluation of the desensitizing efficacy of a paste containing 8% arginine and calcium carbonate. Colgate Sensitive Instant Relief Repair & Prevent Toothpaste starts blocking sensitivity pain instantly*. BMC Oral Health 21, 498 (2021). Table 4 demonstrates a comparison between treatment groups observing better clinical efficacy in managing DH on SCASS. Springer Nature. Ingredients *Potassium Nitrate However, there was no significant treatment difference between dentifrices containing Pro-argin and strontium acetate (p>0.05) at each efficacy interval. This site is intended for healthcare professionals only. 2018;2018:110. Wilcoxon Signed-Rank Test was used to compute mean scores relative to baseline at each time point. Colgate-Palmolive Company 2018. How does Colgate Sensitive Pro-Relief Repair & Prevent work? The first post-treatment measure of SCASS and VAS scores was obtained immediately after removing dentifrices from teeth. Researchers have investigated the clinical efficacy of popular propriety occluding dentifrices containing Pro-argin, strontium acetate, and FCPS formulations for treating DH and have found no adverse effects. Am J Dent. I want to acknowledge the administrative faculty and staff assistants in the Department of Periodontology for facilitation in data collection. Dentifrices-containing Pro-argin showed a significant reduction in DH with mean scores of (3.052.17) followed by strontium acetate (3.751.97) followed by FCPS (5.301.83) one minute after application. YES Somewhat No Another . Thus, 128 participants completed the trial and were statistically analyzed for primary outcome measure of SCASS scores after lost to follow up (Fig. Colgate Sensitive Pro-Relief toothpaste is a revolutionary and one-of-its kind remedy that can provide consumers suffering from Sensitivity the much needed instant and long lasting relief . 2 Docimo et al. Lasting protection with regular use. Google Scholar. J Dent. The Gum Health Physical is a new interactive digital tool you can use to quickly evaluate your patients in-office, and give them a personalized report they can use at home. The findings have revealed that both statistically and clinically significant change in mean scores of DH was observed with Pro-argin and 8% strontium acetate with p<0.05 relative to baseline for immediate and sustained relief from DH using clinical parameters of SCASS and VAS. A comparative clinical study investigating the efficacy of a dentifrice containing 8% strontium acetate and 1040 ppm fluoride in a silica base and a control dentifrice containing 1450 ppm fluoride in a silica base to provide immediate relief of dentin hypersensitivity. 2010;23(Spec No A):14A-9A. J Clin Dent 2009; 20 (Spec Iss): 17-22. Paired sample T-test was used to compute mean scores to observe change relative to baseline at each time point. The makers of Colgate Sensitive Pro-Relief and its rival, Sensodyne Rapid Relief, have been dobbing each other into the health regulator over advertising claims that the toothpastes give users "instant" relief to pain from sensitive teeth. Therefore, this trial was planned to investigate the clinical efficacy of Pro-argin and strontium acetate for immediate pain relief in DH after one minute of topical application to fill the research gap associated with limited published evidence and risk of bias in selection, performance, attrition, and reporting as predicted by Pessoa et al. 2017;2017:2. Cookies policy. These fluorapatite crystals were less susceptible to acidic dissolution than hydroxyapatite crystals and thus were more desirable [13]. Mockdeci H, Polonini H, Martins I, Granato A-P, Raposo N. Evaluation of ex vivo effectiveness of commercial desensitizing dentifrices. Written informed consent was obtained with a signed agreement plan to visit for six weeks at interim efficacy intervals of day three, week two, week four, and week six. In our study, patient compliance related to the recommended time of application and method of the application provided by doctors was controlled by subjecting multiple efficacy intervals and different methods for assessment of the change in pain scores due to DH. Oral dentifrices have been marketed extensively for pain relief in one minute after topical application on sensitive teeth, with the claims of several dentists recommending the formulations containing Pro-argin and 8% strontium acetate. Poster #0742, March 2018 AADR. Colgate Sensitive Pro Relief offers a solution that is clinically proven to relieve sensitivity pain. Colgate Sensitive Pro-Relief works by plugging the channels to block tooth sensitivity and with regular use, it builds a long-lasting protective barrier that acts like a seal against sensitivity.